Micky van de Ven Brace Ends The Toffees' Unbeaten Streak at New Home Ground
The Dutch defender emerged as the initial defender to net twice in a English top-flight game for Spurs since Jan Vertonghen in spring 2013.
Match summary
Micky Van de Ven nods into the net twice in first half
Everton's Jake O'Brien has goal disallowed after VAR review
Senegalese midfielder scores final goal in dying moments
The defeat is the Merseyside club's first at their new ground
Micky van de Ven scored twice as Spurs extended their winning streak on the road in the Premier League and delivered Everton their initial loss at their new home.
Everton were unbeaten in their last five matches at their new ground at Bramley-Moore Dock, having left their historic home behind after more than a century at the conclusion of the previous campaign.
But Spurs captain Van de Ven pounced twice from set-pieces in the first half to place their strong form at risk, and they were failed to mount a comeback before Pape Matar Sarr - set up by ex-Everton forward the Brazilian - nodded in a final goal to put the game to bed.
The Everton defender thought he had equalized the scores five minutes after the defender's opener, glancing a bullet header past Guglielmo Vicario from an set-piece.
The Portuguese striker, meanwhile, missed a handful of opportunities, while Vicario made a series of excellent stops to ensure the London club went five matches on the road unbeaten in the English top flight.
But the video assistant referee intervened, instructing the match official to review the score on the pitchside monitor and the referee ruled that Jack Grealish and Iliman Ndiaye were in an illegal position and had interfered with the Tottenham goalkeeper.
The win elevates the manager's team up to third in the Premier League, a handful of points off local foes and leaders the Gunners.
The Merseyside club stay in 14th position and are half a dozen points ahead of the relegation zone.
Tottenham analysis: The defender excels in duties at each end of the field
Following a drab weekday performance in the Champions League against Monaco, where they mustered a mere attempts on goal, Frank opted for the French striker in attack instead of former Toffees player Richarlison.
The new arrival was unable to influence the game before being replaced for Richarlison after an hour on the field, but it emerged he proved unnecessary in the end.
Defender Van de Ven transformed into an attacking force to be reckoned with.
Spurs' opening strike came from a cleverly executed set-piece play, with Rodrigo Bentancur directing the ball back across the six-yard box for an unmarked the defender to score.
And the captain - filling in as skipper in the Argentine's absence - added his next goal in first-half stoppage time as he rose above Jordan Pickford to nod in.
Van de Ven was just as impressive in defence, partnering effectively with Kevin Danso as the pair dealt excellently with the numerous deliveries sent their way by Everton.
Toffees breakdown: Everton missing finishing touch
The club's new home had been a happy hunting ground, but it seems the freshness may have worn off somewhat and supporters flocked to the gates after Sarr's third for Tottenham.
The break in Everton's winning streak at home won't be a major concern for David Moyes, but their striker situation are.
The forward and the other striker - the Everton's pair of recognised strikers - had netted just a single goal between them before the weekend's match.
And they were failed to contribute to that poor tally on a wet and gloomy night on Merseyside.
Beto's form was epitomized when he opted to overhead kick a clear chance from near the goal, even with having room and time to reposition for a more conventional attempt that would have tested Vicario.
The substitute, too, was unable to influence the game after replacing Beto in the second half.
It wasn't for a shortage of chance. The majority of the home side's offensive moves came through the winger and the forward, who tirelessly whipped threatening crosses into the Spurs penalty area.
What next for both teams?
The Toffees: The team travel to the Stadium of Light in the Premier League on early November at 20:00 GMT.
Tottenham: Spurs travel to St James' Park on late October for their fourth-round Carabao Cup match against the Magpies.